Aches and pains associated with neurological dysfunction such as damaged peripheral nerves are commonly referred to neuropathic pain. Chronic pain is maladaptive has no beneficial biologic significance and is characterized by spontaneous pain e.g.

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nocioceptive and neuropathic processes.1Central poststroke pain is a neuropathic pain syndrome which is a direct con sequence of ischemic damage and is especially challenging to study because it usually observes an unpredictable latent . showed that the use of a cryopneumatic. among individuals with chronic pain neuropathic subtype was. Despite suggestions that phantom joint pain post TJA is a common problem there is limited information about . Neuropathic pain due to CIDP can be treated with antiseizure medications antidepressants such as or analgesics including opiate drugs. Moreover among individuals with chronic pain symptoms a significant proportion 2843 of those experience pain that appears to have a neuropathic component even 1.5 to 3.5 years following surgery.Overall prevalence of NP in TJA was 3.3 to 4.5. 87 Many studies have shown that neuropathic pain is only slightly responsive or not responsive at. Severe pain subjects were negatively impacted by 30 in each outcome compared with mild pain. Pregabalin an alpha2delta ligand is approved for treatment of fibromyalgia FM neuropathic pain NeP due to postherpetic neuralgia PHN diabetic peripheral neuropathy pDPN spinal cord injury and as adjunct therapy for partial onset seizures. In recent years studies have found considerable overlaps between pain . p pDespite suggestions that phantom joint pain post TJA is a common . pronounced disabling fatigue mental and physical postexertional malaise.